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about | nobel prize & l-arginine research

Nobel Prize and L-Arginine Research

A critical breakthrough was made when Harvard and Stanford scientists found that the amino acid L-Arginine converts to Nitric Oxide within the wall of all blood vessels. In 1998, three researchers won the Nobel Prize in Medicine "for their discoveries concerning Nitric Oxide as a signaling molecule. ©The Nobel Foundation

ARGININE ADVANTAGE® - Embraces the new explosion of knowledge on longevity of life supported by the Nobel Prize in Medicine

In 2017, Nobel Prize Winner, Elizabeth Blackburn, PhD., published her book entitled, The Telomere Effect. It has been known for years that your telomeres determine your health and longevity. In your DNA each cell has these telomeres; and, as you age, they get shorter and shorter. When they get too short, you enter the DISEASE SPAN OF YOUR LIFE. That time frame could be from age 50 to 80. If you have cardiovascular disease, you are in this DISEASE SPAN period. There are many reasons for this condition.

 

Dr. Blackburn was awarded the Nobel Prize for medicine for her work on telomeres. What she and research partner Elissa Epel, PhD. discovered is that you can lengthen your telomeres through a healthy lifestyle. In so doing, you can go out of the DISEASE SPAN and back into the HEALTH SPAN of your life.

 

The DISEASE SPAN is a weakness of your immune system which means you are now susceptible to sickness, disease, and early death. This telomere knowledge ends the health risk or the "Roll-of-the-Dice" health risk we have all feared.

 

What's most revealing about the DISEASE SPAN is the effect of lifestyle (stress, diet, exercise, BMI and sleep) on your telomeres. They improve cardiovascular and heart disease. ARGININE ADVANTAGE® is designed to improve these 5 very important health conditions. We did not know how important they were until Dr. Blackburn's research established it. When you have the energy and strength from better blood flow, you can accomplish more and do it easier. This new formula was designed to rebuild the heart muscle which is a treatment for congestive heart disease. ARGININE ADVANTAGE® restores your cardiovascular system and improves your health and quality of life.

L-Arginine Research Links

COLUMBIA UNIVERSITY

In a recent study at Columbia University, researchers called L-Arginine, "The Magic Bullet." Below you'll find the latest research detailing what L-Arginine can do for you.

 

Correction of Endothelial dysfunction: additional effects of exercise training and oral L-Arginine supplementation.

 

40 patients were divided into groups to test the effects of L-Arginine on vasodilation. The goal was to analyze whether L-Arginine has comparable or additive effects to physical exercise. After four weeks of observation and study, researchers concluded that the effectiveness of L-Arginine on vasodilation was similar to that of regular exercise, and that when exercise and L-Arginine supplementation are combined, the effects are even greater.

SPRINGERLINK

Differential inhibition of Human Platelet Aggregation and Thromboxane A2 formation by L-Arginine in Vivo and in Vitro. 

In a study of 20 healthy male volunteers, researchers used L-Arginine and a placebo to determine the effects of L-Arginine on platelet aggregation and Thromboxane A2 formation in Vivo and in Vitro. The results indicated that the L-Arginine/Nitric Oxide pathway is present in human platelets as a Ca2+-dependent anti-aggregatory pathway, and that in vivo the formation of Nitric Oxide from L-Arginine by Endothelial cells may contribute to these platelet-inhibitory effects.

NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION

L-Arginine in the management of Nitric Oxide production.

An in-depth look into five decades' worth of L-Arginine studies shows that L-Arginine improves the management of nitric oxide. It has been demonstrated that intravenous L-Arginine augments Endothelial function by enhancing Vasodilation and reducing Monocyte Adhesion, while oral supplementation demonstrated similar effects as well as improvement of exercise ability in patients.

NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION

L-Arginine supplementation improves exercise capacity

Researchers compared the exercise capacity in healthy subjects and patients not so healthy and investigated whether L-Arginine supplementation might improve exercise capacity. Subjects performed a 6-minute walk test and a maximal bicycle exercise test before and after a 6-week period of placebo intake or L-Arginine supplementation. Unlike with the placebo intake, six weeks of L-Arginine supplementation improved quality of life for the recipients-their submaximal exercise capacity increased, as did their distance walked during the 6-minute walking test.

NATIONAL CENTER FOR BIOTECHNOLOGY

INFORMATION

L-Arginine supplementation improves exercise capacity

Researchers compared the exercise capacity in healthy subjects and patients not so healthy and investigated whether L-Arginine supplementation might improve exercise capacity. Subjects performed a 6-minute walk test and a maximal bicycle exercise test before and after a 6-week period of placebo intake or L-Arginine supplementation. Unlike with the placebo intake, six weeks of L-Arginine supplementation improved quality of life for the recipients-their submaximal exercise capacity increased, as did their distance walked during the 6-minute walking test.

Sciencedirect

Effect of oral L-Arginine supplementation: a meta-analysis of randomized, double-blind, placebo-controlled trials.

Previous studies suggest that L-Arginine, an amino acid and a substrate of Nitric Oxide synthase, may produce higher amounts of Nitric Oxide. Because some studies were performed with limited number of patients with low Nitric Oxide production and therefore limited statistical power with sometimes inconsistent results, we aimed to examine the effect of oral L-Arginine supplementation by conducting a meta-analysis of randomized, double-blind, placebo-controlled trials.

WILEY ONLINE LIBRARY

Erectile dysfunction (ED) - Effect of oral administration of high‐dose nitric oxide donor l‐arginine in men with organic erectile dysfunction: results of a double‐blind, randomized, placebo‐controlled study

 

To determine, in a prospective randomized, double-blind placebo-controlled study, the effect of 6 weeks of high-dose (5 g/day) orally administered nitric oxide (NO) donor l-arginine on men with low nitric oxide production.

MAYO CLINIC

L-ARGININE

 

L-arginine is an amino acid that helps the body build protein. Your body usually makes all the L-arginine it needs. L-arginine is also found in most protein-rich foods, including fish, red meat, poultry, soy, whole grains, beans and dairy products.

As a supplement, L-arginine can be used orally and topically. Because L-arginine acts as a vasodilator, opening (dilating) blood vessels, many people take oral L-arginine to try to treat cardiovascular conditions and erectile dysfunction.